List of United States Senators from South Carolina

South Carolina ratified the Constitution on May 23, 1788. Its Senate seats were declared vacant in July 1861 owing to its secession from the Union. They were again filled from July 1868.

Class 2
Class 2 U.S. Senators belong to the electoral cycle that were elected for two sessions of the U.S. Congress in the first election of 1788 and whose seats in recent years are contested in 1996, 2002, 2008, and 2014.

Class 3
Class 3 U.S. Senators belong to the electoral cycle that were elected for three sessions of the U.S. Congress in the first election of 1788 and whose seats in recent years are contested in 1998, 2004, 2010, and 2016.

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